Nocodazole

Name: Nocodazole
Brand: Hello Bio
SKU: HB3999
Price: 389 USD
Availability: InStock

(HB3999)

Be the first to add a publication

Technical documents: Datasheet

Product overview

Name

Nocodazole

Purity

>98%

Description

Mitosis inhibitor, widely used as a cell cycle synchronizing agent. Enhances HDR efficiency and increases Cas9-mediated gene editing frequencies.

Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (2) References (3)

Write Your Own Review

Biological Data

Biological description

Mitosis inhibitor which which induces microtubule depolymerization in vivo and inhibits tubulin polymerziation. Arrest cell cycle at the G2/M phase. Widely used as a cell cycle synchronizing agent. Enhances homology-directed repair (HDR) efficiency (depending on cell cycle phase) and increases Cas9-mediated gene editing frequencies.

Solubility & Handling

Storage instructions

+4°C

Important

This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

More Info

Dilution

More Info

Chemical Data

Purity

>98%

Molecular Weight

301.3

Chemical structure

Molecular Formula

C₁₄H₁₁N₃O₃S

CAS Number

31430-18-9

PubChem identifier

4122

SMILES

COC(=O)NC1=NC2=CC(=CC=C2N1)C(=O)C1=CC=CS1

InChiKey

KYRVNWMVYQXFEU-UHFFFAOYSA-N

Appearance

White to off-white solid

Technical guides

Understanding purity and quality - a guide for life scientists (159.4 KB)

Inducible CreER and CRISPR/Cas9 mini review

References for Nocodazole

References are publications that support the biological activity of the product

Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery.
Lin et al (25497837) Elife 15(3) : e04766
Read more (PubMedID: 25497837)
Microtubule disruption inhibits autophagosome-lysosome fusion: implications for studying the roles of aggresomes in polyglutamine diseases.
Webb et al (2004) Int J Biochem Cell Biol 36(12) : 2541-50.
Read more (PubMedID: 15325591)
Nanomolar concentrations of nocodazole alter microtubule dynamic instability in vivo and in vitro.
Vasquez et al (1997) Mol Biol Cell 8(6): : 973-85
Read more (PubMedID: 9201709)

Mitosis inhibitor, widely used as a cell cycle synchronizing agent. Enhances HDR efficiency and increases Cas9-mediated gene editing frequencies.

New Products in this Area

Pexidartinib (PLX3397)

HB8991

Potent CSF-1R inhibitor. Widely used microglia-depletion agent.

Order: HB3999
Pack	Price	Qty
50mg	$389

Nocodazole

Product overview

Biological Data

Solubility & Handling

Calculators

Molarity

Dilution

Chemical Data

Technical guides

References for Nocodazole

Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery.

Microtubule disruption inhibits autophagosome-lysosome fusion: implications for studying the roles of aggresomes in polyglutamine diseases.

Nanomolar concentrations of nocodazole alter microtubule dynamic instability in vivo and in vitro.

About you

Tell us about your publication!

Captcha

New Products in this Area

Nocodazole

Product overview

Biological Data

Solubility & Handling

Calculators

Molarity

Dilution

Chemical Data

Technical guides

References for Nocodazole

Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery.

Microtubule disruption inhibits autophagosome-lysosome fusion: implications for studying the roles of aggresomes in polyglutamine diseases.

Nanomolar concentrations of nocodazole alter microtubule dynamic instability in vivo and in vitro.

About you

Tell us about your publication!

Captcha

About you

How can we help you?

New Products in this Area

Related Products