Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. Description:

    Selective TRPC6 channel activator and neurotransmitter re-uptake inhibitor

    Purity:

    >97%

    Pack:
    1mg
    Price:
    $269
    Qty:
  2. Hypotaurine (HB2656)

    Description:

    Non-selective endogenous glycine receptor agonist 

    Purity:

    >95%

    Pack:
    100mg
    Price:
    $106
    Qty:
  3. Description:

    Antibody to IBA1 - calcium binding protein widely used as a marker for microglial cells. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Rabbit
    Clonality: Polyclonal
    Reactivity Tested: Mouse, Rat
    Pack:
    100μL
    Price:
    $320
    Qty:
  4. Pack:
    100μg
    Price:
    $253
    Qty:
  5. Description:

    BET bromodomain inhibitor, also promotes differentiation of hiPSCs into megakaryocytes

    Purity:

    >98%

    Pack:
    50mg
    Price:
    $1,254
    Qty:
  6. IBMX (HB3000)

    Description:

    Non-selective, competitive cAMP and cGMP PDE inhibitor. Facilitates neural progenitor cell differentiation.

    Purity:

    >98%

    Pack:
    100mg
    Price:
    Qty:
    Pack:
    500mg
    Price:
    $138
    Qty:
  7. Pack:
    1mg
    Price:
    $89
    Qty:
    Pack:
    5mg
    Price:
    $283
    Qty:
    Pack:
    25mg
    Price:
    $906
    Qty:
    Pack:
    10mM (add 1ml water)
    Price:
    $37
    Qty:
  8. Ibrutinib (HB4204)

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    Description:

    Potent, selective Bruton's tyrosine kinase (BTK) inhibitor.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $156
    Qty:
    Pack:
    25mg
    Price:
    $469
    Qty:
  9. Pack:
    10mg
    Price:
    $181
    Qty:
    Pack:
    50mg
    Price:
    $726
    Qty:
  10. Pack:
    1mg
    Price:
    $35
    Qty:
    Pack:
    5mg
    Price:
    $119
    Qty:
    Pack:
    10mg
    Price:
    $217
    Qty:
    Pack:
    25mg
    Price:
    $460
    Qty:
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