Non-selective NMDA and mGlu receptor agonist (EC50 values are 17, 43, 110, >1000 and >1000 μM for mGlu5a, mGlu1a, mGlu2, mGlu4a and mGlu6 receptors respectively). Shows excitotoxic actions. Used for cognitive dysfunction models for neurodegenerative disease research.
Solubility & Handling
Solubility overview
Soluble in water (10mM) and in 0.1M NaOH (100mM)
Storage instructions
-20°C (desiccate)
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
These publications cite the use of Ibotenic acid purchased from Hello Bio:
Further development of a liquid chromatography-high-resolution mass spectrometry/mass spectrometry-based strategy for analyzing eight biomarkers in human urine indicating toxic mushroom or Ricinus communis ingestions
Bambauer TP et al (2021) Drug Test Anal 13(9) : 1603-1613
Development and application of a strategy for analyzing eight biomarkers in human urine to verify toxic mushroom or ricinus communis ingestions by means of hydrophilic interaction LC coupled to HRMS/MS