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ICA 121431

(HB1017)
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Product overview

Name ICA 121431
Purity >98%
Description Potent, selective Nav1.3 / Nav1.1 channel inhibitor
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (1)
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Images

ICA 121431 product vial image | Hello Bio
ICA 121431 product vial image | Hello Bio

ICA 121431 product vial image | Hello Bio

ICA 121431 product vial image | Hello Bio

Biological Data

Biological description Potent and selective Nav1.3 and Nav1.1 channel inhibitor (IC50 = 19 nM at Nav1.3). Acts at an inhibitory interaction site.

Solubility & Handling

Solubility overview Soluble in DMSO (100mM)
Storage instructions +4°C
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

Molarity

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Dilution

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Chemical Data

Purity >98%
Chemical name α-Phenyl-N-[4-[(2-thiazolylamino)sulfonyl]phenyl]benzeneacetamide
Molecular Weight 449.55
Chemical structure ICA 121431 [313254-51-2] Chemical Structure
Molecular Formula C23H19N3O3S2
CAS Number 313254-51-2
PubChem identifier 998021
SMILES O=S(C1=CC=C(NC(C(C4=CC=CC=C4)C3=CC=CC=C3)=O)C=C1)(NC2=NC=CS2)=O
InChi InChI=1S/C23H19N3O3S2/c27-22(21(17-7-3-1-4-8-17)18-9-5-2-6-10-18)25-19-11-13-20(14-12-19)31(28,29)26-23-24-15-16-30-23/h1-16,21H,(H,24,26)(H,25,27)
InChiKey URSQNPPONHUJDL-UHFFFAOYSA-N
MDL number MFCD00992334

References for ICA 121431

References are publications that support the biological activity of the product

  • Voltage sensor interaction site for selective small molecule inhibitors of voltage-gated sodium channels.

    McCormack K et al (2013) Proc Natl Acad Sci U S A 110(29) : E2724-32.
    Read more (PubMedID: 23818614)

1 Item

Grouped product items
Order: HB1017
Pack PriceQty
1mg
$35
5mg
$119
10mg
$217
25mg
$460
Potent, selective Nav1.3 / Nav1.1 channel inhibitor
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

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