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Images
ICA 121431 product vial image | Hello Bio
ICA 121431 product vial image | Hello Bio
Biological Data
| Biological description | Potent and selective Nav1.3 and Nav1.1 channel inhibitor (IC50 = 19 nM at Nav1.3). Acts at an inhibitory interaction site. |
Solubility & Handling
| Storage instructions | +4°C |
| Solubility overview | Soluble in DMSO (100mM) |
| Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use |
Chemical Data
| Chemical name | α-Phenyl-N-[4-[(2-thiazolylamino)sulfonyl]phenyl]benzeneacetamide |
| Chemical structure | ![ICA 121431 [313254-51-2] Chemical Structure](data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR4nGP6zwAAAgcBApocMXEAAAAASUVORK5CYII= "ICA 121431 [313254-51-2]") |
| Molecular Formula | C23H19N3O3S2 |
| PubChem identifier | 998021 |
| SMILES | O=S(C1=CC=C(NC(C(C4=CC=CC=C4)C3=CC=CC=C3)=O)C=C1)(NC2=NC=CS2)=O |
| InChi | InChI=1S/C23H19N3O3S2/c27-22(21(17-7-3-1-4-8-17)18-9-5-2-6-10-18)25-19-11-13-20(14-12-19)31(28,29)26-23-24-15-16-30-23/h1-16,21H,(H,24,26)(H,25,27) |
| InChiKey | URSQNPPONHUJDL-UHFFFAOYSA-N |
References for ICA 121431
References are publications that support the biological activity of the product
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Voltage sensor interaction site for selective small molecule inhibitors of voltage-gated sodium channels.
McCormack K et al (2013) Proc Natl Acad Sci U S A 110(29) : E2724-32.
Potent, selective Nav1.3 / Nav1.1 channel inhibitor
![ICA 121431 [313254-51-2] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb1017.png "ICA 121431 [313254-51-2]")
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