Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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Items 681-690 of 719

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  1. VX 745 (HB1309)

    Description:

    Potent, selective p38α MAPK inhibitor

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $213
    Qty:
    Pack:
    50mg
    Price:
    $822
    Qty:
  2. Pack:
    50mg
    Price:
    $723
    Qty:
  3. Wedelolactone (HB4124)

    Description:

    Selective IKKα and IKKβ kinase activity inhibitor. NF-κB inhibitor.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $134
    Qty:
    Pack:
    5mg
    Price:
    $384
    Qty:
  4. WHI-P 154 (HB1431)

    Description:

    Non-selective JAK3 inhibitor and potent EGFR inhibitor. Induces neural progenitor cell differentiation.

    Purity:

    >99%

    Pack:
    5mg
    Price:
    $85
    Qty:
    Pack:
    25mg
    Price:
    $307
    Qty:
  5. Pack:
    5mg
    Price:
    $94
    Qty:
    Pack:
    25mg
    Price:
    $365
    Qty:
  6. Pack:
    50mg
    Price:
    $842
    Qty:
  7. Wnt-C59 (HB3155)

    Description:

    Highly potent PORCN inhibitor. Induces iPSC cardiomyocytes differentiation.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $271
    Qty:
    Pack:
    50mg
    Price:
    $1,056
    Qty:
  8. Wogonin (HB4126)

    Description:

    Cell permeable COX-2 inhibitor. Increase NO production.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $101
    Qty:
    Pack:
    25mg
    Price:
    $397
    Qty:
  9. Wortmannin (HB2778)

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    Description:

    Potent, selective, irreversible PI3-K inhibitor

    Purity:

    >99%

    Pack:
    1mg
    Price:
    Qty:
    Pack:
    5mg
    Price:
    $257
    Qty:
    Pack:
    10mg
    Price:
    $475
    Qty:
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