Wiskostatin

Name: Wiskostatin
SKU: HB0658
Price: 833 USD
Availability: InStock

(HB0658)

Be the first to add a publication

Technical documents: Datasheet

Product overview

Name

Wiskostatin

Purity

>99%

Description

Potent, selective N-WASP inhibitor

Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) References (3)

Write Your Own Review

Biological Data

Biological description

Potent and selective neural Wiskott-Aldrich syndrome protein (N-WASP) inhibitor that interacts with GTPase- binding domain. Inhibits Arp2/3 complex activation. Decreases cellular ATP levels and inhibits cytokinesis but not mitosis. A carbazole derivative.

Solubility & Handling

Storage instructions

+4°C

Solubility overview

Soluble in DMSO (100mM)

Important

This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

More Info

Dilution

More Info

Chemical Data

Purity

>99%

Chemical name

3,6-Dibromo-α-[(dimethylamino)methyl ]-9H-cabazole-9-ethanol

Molecular Weight

426.15

Chemical structure

Molecular Formula

C₁₇H₁₈Br₂N₂O

CAS Number

253449-04-6

PubChem identifier

2775510

SMILES

BrC(C=C3)=CC1=C3N(CC(O)CN(C)C)C2=C1C=C(Br)C=C2

InChiKey

XUBJEDZHBUPBKL-UHFFFAOYSA-N

Technical guides

Understanding purity and quality - a guide for life scientists (159.4 KB)

References for Wiskostatin

References are publications that support the biological activity of the product

Inhibition of cytokinesis by wiskostatin does not rely on N-WASP/Arp2/3 complex pathway.
Bompard G et al (2008) BMC Cell Biol 9 : 42
Read more (PubMedID: 18667055)
N-WASP inhibitor wiskostatin nonselectively perturbs membrane transport by decreasing cellular ATP levels.
Guerriero CJ et al (2007) Am J Physiol Cell Physiol 292(4) : C1562-6.
Read more (PubMedID: 17092993)
Chemical inhibition of N-WASP by stabilization of a native autoinhibited conformation.
Peterson JR et al (2004) Nat Struct Mol Biol 11(8) : 747-55.
Read more (PubMedID: 15235593)

Potent, selective N-WASP inhibitor

Order: HB0658
Pack	Price	Qty
50mg	$833

Wiskostatin

Product overview

Biological Data

Solubility & Handling

Calculators

Molarity

Dilution

Chemical Data

Technical guides

References for Wiskostatin

Inhibition of cytokinesis by wiskostatin does not rely on N-WASP/Arp2/3 complex pathway.

N-WASP inhibitor wiskostatin nonselectively perturbs membrane transport by decreasing cellular ATP levels.

Chemical inhibition of N-WASP by stabilization of a native autoinhibited conformation.

About you

Tell us about your publication!

Captcha

New Products in this Area

Wiskostatin

Product overview

Biological Data

Solubility & Handling

Calculators

Molarity

Dilution

Chemical Data

Technical guides

References for Wiskostatin

Inhibition of cytokinesis by wiskostatin does not rely on N-WASP/Arp2/3 complex pathway.

N-WASP inhibitor wiskostatin nonselectively perturbs membrane transport by decreasing cellular ATP levels.

Chemical inhibition of N-WASP by stabilization of a native autoinhibited conformation.

About you

Tell us about your publication!

Captcha

About you

How can we help you?

New Products in this Area