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W-5 hydrochloride

(HB0649)
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Product overview

Name W-5 hydrochloride
Alternative names W-5; W5
Purity >98%
Description Calmodulin (CaM) antagonist
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (3)
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Biological Data

Biological description Calmodulin (CaM) antagonist. Reverses the inhibitory effect of insulin via dibutytyl cAMP. A chlorine-deficient inactive analogue of W-7.

Solubility & Handling

Solubility overview Soluble in DMSO (50mM) or water (10mM)
Storage instructions Room temperature
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >98%
Chemical name N-(6-Aminohexyl)-1-naphthalenesulfonamide hydrochloride
Molecular Weight 342.88
Chemical structure W-5 hydrochloride [61714-25-8] Chemical Structure
Molecular Formula C16H22N2O2S.HCl
CAS Number 61714-25-8
PubChem identifier 173829
SMILES Cl.NCCCCCCNS(=O)(=O)C1=C2C=CC=CC2=CC=C1
InChiKey HOCSVIGHWPLMFC-UHFFFAOYSA-N

References for W-5 hydrochloride

References are publications that support the biological activity of the product

  • W-5 and quin 2-AM reverse the inhibitory effect of insulin on lipolysis due to dibutyryl cAMP.

    Goko H et al (1999) Diabetes Res Clin Pract 44(2) : 101-6.
    Read more (PubMedID: 10414928)

  • Effect of calmodulin antagonists on auxin-induced elongation.

    Raghothama KG et al (1985) Plant Physiol 79(1) : 28-33.
    Read more (PubMedID: 16664387)

  • N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation.

    Hidaka H et al (1981) Proc Natl Acad Sci U S A 78(7) : 4354-7.
    Read more (PubMedID: 6945588)

3 Item(s)

Grouped product items
Order: HB0649
Pack PriceQty
25mg
$274
Calmodulin (CaM) antagonist
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

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