Product overview

Name Wogonin
Purity >98%
Description Cell permeable COX-2 inhibitor. Increase NO production.
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Biological Data

Biological description Anti-inflammatory. Increases nitric oxide (NO) production. Inhibits PGE2, cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS; NOS II). Antioxidant. Anti-viral. Shows anti-hepatitis B virus activity. MCP-1 inhibitor. Shows anxiolytic effect through modulation of the GABA(A) receptor complex. Antifungal. Neuroprotective. Anticancer compound. Apoptosis and cell cycle arrest inducer. Sensitizes TNFalpha- and TRAIL-induced apoptosis. Antiangiogenic. NF-kappaB inhibitor. Telomerase activity inhibitor. CDK9 inhibitor. PI3K-AKT pathway modulator. Autophagy inducer.

Solubility & Handling

Storage instructions +4°C
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Purity >98%
Chemical name 5,7-Dihydroxy-8-methoxyflavone
Molecular Weight 284.3
Chemical structure Wogonin [632-85-9] Chemical Structure
CAS Number 632-85-9
SMILES COc1c(O)cc(O)c2C(=O)C=C(Oc12)c3ccccc3
InChiKey XLTFNNCXVBYBSX-UHFFFAOYSA-N
Appearance Yellow solid