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Biological Data
| Biological description | Anti-inflammatory. Increases nitric oxide (NO) production. Inhibits PGE2, cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS; NOS II). Antioxidant. Anti-viral. Shows anti-hepatitis B virus activity. MCP-1 inhibitor. Shows anxiolytic effect through modulation of the GABA(A) receptor complex. Antifungal. Neuroprotective. Anticancer compound. Apoptosis and cell cycle arrest inducer. Sensitizes TNFalpha- and TRAIL-induced apoptosis. Antiangiogenic. NF-kappaB inhibitor. Telomerase activity inhibitor. CDK9 inhibitor. PI3K-AKT pathway modulator. Autophagy inducer. |
Solubility & Handling
| Storage instructions | +4°C |
| Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
| Chemical name | 5,7-Dihydroxy-8-methoxyflavone |
| Chemical structure | ![Wogonin [632-85-9] Chemical Structure](data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR4nGP6zwAAAgcBApocMXEAAAAASUVORK5CYII= "Wogonin [632-85-9]") |
| SMILES | COc1c(O)cc(O)c2C(=O)C=C(Oc12)c3ccccc3 |
| InChiKey | XLTFNNCXVBYBSX-UHFFFAOYSA-N |
Cell permeable COX-2 inhibitor. Increase NO production.
![Wogonin [632-85-9] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb4126.png "Wogonin [632-85-9]")
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