Nuclear Receptors
Nuclear hormone receptors (nuclear receptors) are specialized transcription factors which bind to specific sequences of DNA of particular target genes. They regulate transcription of these target genes in response to a variety of endogenous ligands. Nuclear receptors are classified into two major subfamilies: steroid and non-steroid hormone receptors. Steroid hormone receptors include receptors for estrogen (ER), androgen, glucocorticoid, mineralocorticoid and progesterone. Examples of non-steroid hormone receptors include thyroid receptors, retinoic acid receptors and peroxisome proliferator-activated receptors (PPAR). Researchers can make big savings on Hello Bio's Nuclear Receptors agonists, antagonists and modulators (e.g. tamoxifen, 4-OHT, fulvestrant, DPN, PPT), our prices are around 25-50% less than other suppliers.
View products: Aryl hydrocarbon receptor | Estrogen and related | Liver X and farnesoid X receptors (LXR/FXR) | Glucocorticoid Mineralocorticoid | Other | PPAR | Progesterone
A 769662 (HB1351)
Description:Potent, reversible AMPK activator. Inhibits MSC proliferation.
Purity:>98%
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A83-01 (HB3218)
Description:Selective TGF-βRI (ALK5), ALK4 and ALK7 inhibitor. Maintains human hiPSC self renewal, 3D growth matrix component and promotes long-term organoid growth. Aids fibroblast to NSC/cardiomyocyte reprogramming.
Purity:>98%
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17-AAG (HB3599)
Description:Selective Hsp90 inhibitor. Also protects neuroprogenitor cells against apoptosis.
Purity:>98%
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(+)-Abscisic acid (HB4674)
Description:Phytohormone and endogenous lanthionine synthetase C-like 2 (LANCL2) ligand
Purity:>99%
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Ac-Arg-Leu-Arg-AMC (HB3733)
Description:Fluorogenic tri-peptide substrate. Useful for measuring trypsin-like 20S proteasome peptidase activity.
Purity:>97%
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Acetomycin (HB3734)
Description:Antibiotic with antibacterial, antifungal and antiprotozoal activity
Purity:>98%
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Acridine Orange hydrochloride (HB0699)
Description:Cell permeable fluorescent nucleic acid binding dye
