Product overview

Name Ac-Arg-Leu-Arg-AMC
Description Fluorogenic tri-peptide substrate. Useful for measuring trypsin-like 20S proteasome peptidase activity.
Purity >97%
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Biological Data

Biological description Fluorogenic tri-peptide substrate for measuring the trypsin-like peptidase activity of the 20S proteasome. It is cleaved exclusively at the amide R-AMC bond to release fluorescent product. Shows low Km and high specific activity. Excitation: 380nm. Emission: 460nm. This substrate is useful for inhibitor screening and kinetic analysis.

Solubility & Handling

Storage instructions +4°C
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Molecular Weight 642.8
Chemical structure Ac-Arg-Leu-Arg-AMC [929903-87-7] Chemical Structure
CAS Number 929903-87-7
InChiKey CEEMPRHZPRGAAK-RGRVRPFLSA-N
Appearance Solid lyophilized powder