G protein coupled receptors
G-protein-coupled receptors (also known as GPCRs, transmembrane receptors, or 7-TM receptors), are integral membrane proteins that contain seven membrane-spanning domains (helices). They are coupled to heterotrimeric G proteins on the intracellular side of the cell membrane. Ligand binding causes a conformational change in the GPCR, that is then transmitted to the G protein, activating a signal transduction pathway. Researchers can save up to 50% on GPCR receptor agonists, antagonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.
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(R,S)-MCPG sodium salt (HB0038)
Description:Water soluble, non-selective group I and II mGluR antagonist
Purity:>98%
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MDL100907 hydrochloride (Water soluble) (HB12412)
Description:Potent and selective 5-HT2A receptor antagonist. Water soluble.
Purity:>98%
- Description:
Inhibits α-MSH release inhibitors. Also increase dopamine levels.
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Metergoline (HB1623)
Description:5-HT1/5-HT2 antagonist. Shows affinity for 5-HT6 and 5-HT7.
Purity:>98%
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Mianserin hydrochloride (HB1658)
Description:Non-selective 5-HT2 receptor antagonist. Shows activity at other receptors.
Purity:>99%
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MK-571 sodium salt (HB3976)
Description:Selective leukotriene LTD4 receptor antagonist. Potent MRP1 inhibitor.
Purity:>97%
