G protein coupled receptors

G-protein-coupled receptors (also known as GPCRs, transmembrane receptors, or 7-TM receptors), are integral membrane proteins that contain seven membrane-spanning domains (helices). They are coupled to heterotrimeric G proteins on the intracellular side of the cell membrane. Ligand binding causes a conformational change in the GPCR, that is then transmitted to the G protein, activating a signal transduction pathway. Researchers can save up to 50% on GPCR receptor agonists, antagonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.

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    Fluorimetric reagent. Catecholamine metabolite.

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    >99%

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    Caged glutamate that rapidly and efficiently releases glutamate when photolysed

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    >98%

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    Invertebrate neurotransmitter. Chemogenetic DmOctβ1 receptor activator.

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    >99%

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  8. Perlapine (HB4889)

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    Effective agonist for muscarinic-based DREADDs in vitro and in vivo. Non-CNO chemogenetic actuator

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