G protein coupled receptors

G-protein-coupled receptors (also known as GPCRs, transmembrane receptors, or 7-TM receptors), are integral membrane proteins that contain seven membrane-spanning domains (helices). They are coupled to heterotrimeric G proteins on the intracellular side of the cell membrane. Ligand binding causes a conformational change in the GPCR, that is then transmitted to the G protein, activating a signal transduction pathway. Researchers can save up to 50% on GPCR receptor agonists, antagonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.

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  1. Description:

    Potent dopamine D4 receptor partial agonist

    Purity:

    >99%

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    £307
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    £61
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    £255
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  4. L-AP4 (HB0370)

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    Description:

    L-AP4 is a selective group III mGluR agonist which inhibits synaptic transmission.

    Purity:

    >99%

    Pack:
    5mg
    Price:
    £67
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    £131
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    25mg
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    10mg
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    25mM (add 1ml water)
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    £94
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  6. Description:

    5-HT1A partial agonist

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    10mg
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    £60
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    £216
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  7. BRL 54443 (HB1664)

    Description:

    Potent 5-ht1E/1F receptor agonist

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    10mg
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    £80
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    £245
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