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Images (R,S)-MCPG sodium salt product vial image | Hello Bio
(R,S)-MCPG sodium salt product vial image | Hello Bio Biological Data Biological description Water soluble non-selective group I and II mGluR antagonist.
Also competitive antagonist of ACPD sensitive receptors.
Shows no effect on locomotor activity.
(R,S)-MCPG and (S)-MCPG sodium salt also available. (S)-MCPG also available.
Solubility & Handling Solubility overview Soluble in water (100mM)
Storage instructions Room temperature
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Chemical Data Chemical name (RS )-α-Methyl-4-carboxyphenylglycine disodium salt
Chemical structure
Molecular Formula C10 H9 NNa2 O4
PubChem identifier 90488871
SMILES NC(C)(C(=O)O[Na])c1ccc(cc1)C(=O)O
InChiKey YGOTXTUQJLFNHB-UHFFFAOYSA-L
References for (R,S)-MCPG sodium salt References are publications that support the biological activity of the product
The metabotropic glutamate receptor antagonist (RS)-MCPG produces hyperlocomotion in amphetamine pre-exposed rats. Kim JH et al (1998) Neuropharmacology 37(2) : 189-97. MCPG antagonizes metabotropic glutamate receptors but not long-term potentiation in the hippocampus. Manzoni OJ et al (1994) Eur J Neurosci 6(6) : 1050-4. Competitive antagonism at metabotropic glutamate receptors by (S)-4-carboxyphenylglycine and (RS)-alpha-methyl-4-carboxyphenylglycine. Eaton SA et al (1993) Eur J Pharmacol 244(2) : 195-7.
Water soluble, non-selective group I and II mGluR antagonist
![(R,S)-MCPG sodium salt [1303994-09-3] Chemical Structure](https://cdn.hellobio.com/media/catalog/product//h/b/hb0038.png "(R,S)-MCPG sodium salt [1303994-09-3]")
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