G protein coupled receptors

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G-protein-coupled receptors (also known as GPCRs, transmembrane receptors, or 7-TM receptors), are integral membrane proteins that contain seven membrane-spanning domains (helices). They are coupled to heterotrimeric G proteins on the intracellular side of the cell membrane. Ligand binding causes a conformational change in the GPCR, that is then transmitted to the G protein, activating a signal transduction pathway. Researchers can save up to 50% on GPCR receptor agonists, antagonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.

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  1. Description:

    Novel, inactive photocaged derivative of raseglurant which can be uncaged with violet light. Shows light-dependent analgesic activity in vivo.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $66
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    Pack:
    5mg
    Price:
    $312
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  2. Description:

    Novel, intracellular covalent chemokine CCR2 negative allosteric modulator (NAM). Binds irreversibly.

    Pack:
    50μg
    Price:
    $275
    Qty:
  3. Pack:
    10mg
    Price:
    $123
    Qty:
    Pack:
    50mg
    Price:
    $488
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  4. Pack:
    10mg
    Price:
    $147
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    Pack:
    50mg
    Price:
    $602
    Qty:
  5. Pack:
    50mg
    Price:
    $495
    Qty: