G protein coupled receptors
G-protein-coupled receptors (also known as GPCRs, transmembrane receptors, or 7-TM receptors), are integral membrane proteins that contain seven membrane-spanning domains (helices). They are coupled to heterotrimeric G proteins on the intracellular side of the cell membrane. Ligand binding causes a conformational change in the GPCR, that is then transmitted to the G protein, activating a signal transduction pathway. Researchers can save up to 50% on GPCR receptor agonists, antagonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.
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Escitalopram oxalate (HB1804)
Description:Selective serotonin reuptake inhibitor (SSRI)
Purity:>99%
Fluoxetine hydrochloride (HB1600)
Description:Selective 5-HT uptake inhibitor. Affects differentiation of NSCs.
Purity:>98%
Fluvoxamine maleate (HB2138)
Description:Selective serotonin reuptake inhibitor and σ1 receptor agonist
Purity:>98%
Anti-GAT1 Antibody ValidAbâ„¢ (HB7632)
Description:Antibody to GAT1 - GABA reuptake transporter and marker for GABAergic interneurones. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: RabbitClonality: PolyclonalReactivity Tested: Mouse, RatGBR 12909 dihydrochloride (HB1812)
Description:Potent, competitive dopamine uptake inhibitor
Purity:>98%
KB-R7943 mesylate (HB1133)
Description:Selective, reverse mode Na+ / Ca2+ exchange inhibitor
Purity:>99%
Milnacipran hydrochloride (HB1759)
Description:5-HT and norepinephrine re-uptake inhibitor (SNRI)
Purity:>99%
N-Arachidonylglycine (NAGly) (HB0439)
Description:Endogenous GLYT2 inhibitor / Cav3.1 / 3.2 / 3.3 current inhibitor