G protein coupled receptors
G-protein-coupled receptors (also known as GPCRs, transmembrane receptors, or 7-TM receptors), are integral membrane proteins that contain seven membrane-spanning domains (helices). They are coupled to heterotrimeric G proteins on the intracellular side of the cell membrane. Ligand binding causes a conformational change in the GPCR, that is then transmitted to the G protein, activating a signal transduction pathway. Researchers can save up to 50% on GPCR receptor agonists, antagonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.
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Paroxetine hydrochloride (HB0478)
Description:Potent, selective serotonin reuptake inhibitor. Selective GRK2 inhibitor.
Purity:>99%
- Description:
Phosphatase Inhibitor Cocktail powder for use in cell lysates and tissue extracts including samples containing detergents.
Sertraline hydrochloride (HB1717)
Description:Potent, selective 5-HT re-uptake inhibitor (SSRI)
Purity:>98%
SKF 89976A hydrochloride (HB0976)
Description:Potent, selective, competitive GAT-1 GABA uptake inhibitor
Purity:>99%
Tetrabenazine (HB1711)
Description:Potent inhibitor of vesicular monoamine transport; depletes 5-HT stores
Purity:>98%
UCPH 101 (HB0630)
Description:UCPH-101 is a potent, selective, non-competitive EAAT1 inhibitor
Purity:>98%