Product overview

Name N-Arachidonyl-L-alanine
Purity >98%
Description GLYT2 / GLYT2(EL2) inhibitor
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Biological Data

Biological description GLYT2 and GLYT2(EL2) inhibitor (IC30 values are 5.9 and 6.0 µM). Displays little or no activity at GLYT1 (IC30 = >30 µM). Inhibits pain.

Solubility & Handling

Storage instructions -20°C (desiccate)
Solubility overview Soluble in DMSO (50mM) or ethanol (50mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.



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Chemical Data

Purity >98%
Chemical name 2-(Icosa-5,8,11,14-tetraenoylamino)propanoic acid
Molecular Weight 375.6
Chemical structure N-Arachidonyl-L-alanine  [401941-73-9] Chemical Structure
Molecular Formula C23H37NO3
CAS Number 401941-73-9
PubChem identifier 53394356

References for N-Arachidonyl-L-alanine

References are publications that support the biological activity of the product
  • Extracellular loops 2 and 4 of GLYT2 are required for N-arachidonylglycine inhibition of glycine transport.

    Edington AR et al (2009) J Biol Chem 284(52) : 36424-30.
  • Identification of a new class of molecules, the arachidonyl amino acids, and characterization of one member that inhibits pain.

    Huang SM et al (2001) J Biol Chem 276(46) : 42639-44.

2 Item(s)