Product overview

Name Fluvoxamine maleate
Description Selective serotonin reuptake inhibitor and σ1 receptor agonist
Alternative names NSC 309469
Purity >98%
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Biological Data

Biological description Selective serotonin reuptake inhibitor and σ1 receptor agonist (Ki = 36 nM at σ1). Shows antidepressant and anxiolytic activity. Active in vivo.

Solubility & Handling

Storage instructions +4°C (desiccate)
Solubility overview Soluble in water (10mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Chemical name (E)-5-Methoxy-1-[4-(trifluoromethyl )phenyl]-1-pentanone-O-(2-aminoethyl)oxime maleate
Molecular Weight 434.41
Chemical structure Fluvoxamine maleate [61718-82-9] Chemical Structure
Molecular Formula C15H21F3N2O2.C4H4O4
CAS Number 61718-82-9
PubChem identifier 9560989
SMILES COCCCC/C(=N\OCCN)/C1=CC=C(C=C1)C(F)(F)F.C(=C\C(=O)O)\C(=O)O
InChi InChI=1S/C15H21F3N2O2.C4H4O4/c1-21-10-3-2-4-14(20-22-11-9-19)12-5-7-13(8-6-12)15(16,17)18;5-3(6)1-2-4(7)8/h5-8H,2-4,9-11,19H2,1H3;1-2H,(H,5,6)(H,7,8)/b20-14+;2-1-
InChiKey LFMYNZPAVPMEGP-PIDGMYBPSA-N
MDL number MFCD00269809
Appearance White solid

References for Fluvoxamine maleate

References are publications that support the biological activity of the product
  • Interactions of selective serotonin reuptake inhibitors with subtypes of sigma receptors in rat brain.

    Narita et al (1996) Eur J Pharmacol 307(1) : 117-9
  • Fluvoxamine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in depressive illness.

    Benfield (1986) Drugs 32(4) : 313-34
  • Fluvoxamine, a specific 5-hydroxytryptamine uptake inhibitor.

    Claassen et al (1977) Br J Pharmacol 60(4) : 505-16

3 Item(s)