G protein coupled receptors
G-protein-coupled receptors (also known as GPCRs, transmembrane receptors, or 7-TM receptors), are integral membrane proteins that contain seven membrane-spanning domains (helices). They are coupled to heterotrimeric G proteins on the intracellular side of the cell membrane. Ligand binding causes a conformational change in the GPCR, that is then transmitted to the G protein, activating a signal transduction pathway. Researchers can save up to 50% on GPCR receptor agonists, antagonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.
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Resveratrol (HB4055)
Description:Potent phenolic antioxidant with many biological actions. COX-1 inhibitor.
Purity:>98%
RG 108 (HB1377)
Description:Non-nucleoside DNA methyltransferase inhibitor. Enhances iPSC generation efficiency.
Purity:>99%
Riluzole (HB6093)
Description:Na+ channel blocker / glutamate inhibitor. TREK-1 K2P channel activator.
Purity:>98%
Riluzole hydrochloride (HB0548)
Description:Na+ channel blocker / glutamate inhibitor. TREK-1 K2P channel activator. Water soluble.
Purity:>98%
Ro 25-6981 maleate (HB0554)
Description:Selective negative allosteric modulator of GluN2B (NR2B) containing NMDARs
Purity:>98%
Ro 32-0432 hydrochloride (HB4820)
Description:Potent, selective PKC inhibitor. GRK inhibitor.
Purity:>98%