5-HT2A and D2 receptor antagonist (Ki values are 0.4, 1.3, 6.7 and 7.5 nM at 5-HT2A , D2, D3 and D5 receptors respectively). Also shows affinity for α1 and α2 and H1 receptors. Atypical antipsychotic. Active in vivo.
Solubility & Handling
Storage instructions
+4°C
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Long-term effects of olanzapine, risperidone, and quetiapine on dopamine receptor types in regions of rat brain: implications for antipsychotic drug treatment.
Tarazi FI et al (2001) J Pharmacol Exp Ther 297(2) : 711-7.