G protein coupled receptors
G-protein-coupled receptors (also known as GPCRs, transmembrane receptors, or 7-TM receptors), are integral membrane proteins that contain seven membrane-spanning domains (helices). They are coupled to heterotrimeric G proteins on the intracellular side of the cell membrane. Ligand binding causes a conformational change in the GPCR, that is then transmitted to the G protein, activating a signal transduction pathway. Researchers can save up to 50% on GPCR receptor agonists, antagonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.
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Pyripyropene A (HB4044)
Description:Highly specific acyl-coenzyme A cholesterol acetyltransferase 2 inhibitor
Purity:>95%
QNZ 46 (HB0541)
Description:GluN2C/D selective, non-competitive NMDA receptor antagonist
Purity:>98%
Quetiapine hemifumarate (HB1803)
Description:5-HT2 and D2 antagonist. Atypical antipsychotic.
Purity:>99%
Q-VD-OPh (HB4048)
Description:Cell permeable, irreversible and non-toxic pan-caspase inhibitor
Purity:>95%