Potent and selective protein kinase C inhibitor (IC50 values are 21, 9, 28, 31, 37 and 108 nM for PKC, PKC-α, PKC-β1, PKC-β2, PKC-γ and PKC-ε respectively). Displays 10 -and 4- fold selectivity for PKC-α and PKC-β1 over PKC-ε respectively. Also a G protein-coupled receptor kinase 5 inhibitor. Cell permeable. Displays anti-inflammatory properties.
Solubility & Handling
Solubility overview
Soluble in DMSO
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Understanding purity and quality - a guide for life scientists