Potent and selective protein kinase C inhibitor (IC50 values are 21, 9, 28, 31, 37 and 108 nM for PKC, PKC-α, PKC-β1, PKC-β2, PKC-γ and PKC-ε respectively). Displays 10 -and 4- fold selectivity for PKC-α and PKC-β1 over PKC-ε respectively. Also a G protein-coupled receptor kinase 5 inhibitor. Cell permeable. Displays anti-inflammatory properties.
Solubility & Handling
Solubility overview
Soluble in DMSO
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Understanding purity and quality - a guide for life scientists