Potent and selective protein kinase C (PKC) inhibitor (IC50 = 21 nM). Selective for PKC-α over PKC-βI, PKC-βII, PKC-γ and PKC-ε (IC50 values are 9, 28, 31, 37 and 108 nM respectively). Also a GRK inhibitor (IC50 values are 29, 3.6 and 16μM respectively). Inhibits T cell proliferation, interleukin-2 (IL-2) secretion and IL-2 receptor expression. Cell permeable.
Solubility & Handling
Storage instructions
-20°C
Solubility overview
Soluble in DMSO or methanol.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
![Ro 32-0432 hydrochloride [1145333-02-4] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb4820_2.png "Ro 32-0432 hydrochloride [1145333-02-4]")
Understanding purity and quality - a guide for life scientists
