Ligand-gated ion channel
Ligand-gated ion channels (also known as ionotropic receptors) are transmembrane ion channel proteins that allow passage of ions upon activation by a specific chemical. Ligand-gated ion channels include ionotropic glutamate receptors (AMPA, kainate and NMDA receptors), GABAA, GABAA-ρ, Glycine, 5-HT3, HCN, acetylcholine nicotinic and purinergic (P2X) receptors. Commonly used ligands include D-AP5, NBQX, kainic acid, and gabazine. Researchers can save up to 50% on ligand-gated ion channel (ionotropic receptor) agonists, antagonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.
View products: Ionotropic glutamate | ACh Nicotinic | AMPA | GABAA | Glycine | 5-HT3 | Kainate | NMDA | P2X | Neuroscience Research Tools
Methyllycaconitine citrate (MLA) (HB2026)
Description:Potent, selective α7 nicotinic receptor antagonist
Purity:>95%
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MG132 (HB4135)
Description:Potent, cell-permeable proteasome inhibitor. Calpain inhibitor. Apoptosis inducer.
Purity:>95%
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Mibefradil dihydrochloride (HB1226)
Description:Potent, reversible T- / L-type Ca2+ channel blocker
Purity:>95%
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Mifepristone (HB2783)
Description:Potent glucocorticoid and progesterone receptor antagonist. Also used for gene editing as a mifepristone inducible Cas9 and Cpf1 CRISPR effector.
Purity:>99%
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Milnacipran hydrochloride (HB1759)
Description:5-HT and norepinephrine re-uptake inhibitor (SNRI)
Purity:>99%
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MK-2206 dihydrochloride (HB5934)
Description:Highly selective, pan-Akt inhibitor. Autophagy and apoptosis inducer. Orally bioavailable.
Purity:>98%
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MK-571 sodium salt (HB3976)
Description:Selective leukotriene LTD4 receptor antagonist. Potent MRP1 inhibitor.
Purity:>97%
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(-)-MK 801 maleate (HB0003)
Description:NMDA receptor antagonist. Less active enantiomer of (+)-MK 801.
Purity:>99%
