mTOR activator and autophagy inhibitor. Cell permeable. Markedly increases the LC3II/LC3I ratio in a dose- and time- dependent manner by inhibition of the fusion between autophagosomes and lysosomes, and without increasing the autophagic flux. Less toxic than other autophagy inhibitors.
Solubility & Handling
Solubility overview
Soluble in DMSO (50 mM with gentle warming)
Storage instructions
+4°C
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use