MHY 1485

Name: MHY 1485
Brand: Hello Bio
SKU: HB7154
Price: 58 USD
Availability: InStock

(HB7154)

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Technical documents: Datasheet

Product overview

Name

MHY 1485

Alternative names

MHY1485

Purity

>98%

Description

mTOR activator and autophagy inhibitor. Cell-permeable.

Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) References (3)

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Biological Data

Biological description

mTOR activator and autophagy inhibitor. Cell permeable. Markedly increases the LC3II/LC3I ratio in a dose- and time- dependent manner by inhibition of the fusion between autophagosomes and lysosomes, and without increasing the autophagic flux. Less toxic than other autophagy inhibitors.

Solubility & Handling

Storage instructions

+4°C

Solubility overview

Soluble in DMSO (50 mM with gentle warming)

Important

This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

Molarity

More Info

Dilution

More Info

Chemical Data

Purity

>98%

Chemical name

4,6-Bis(morpholin-4-yl)-N-(4-nitrophenyl)-1,3,5-triazin-2-amine

Molecular Weight

387.39

Chemical structure

Molecular Formula

C₁₇H₂₁N₇O₄

CAS Number

326914-06-1

PubChem identifier

2834965

SMILES

[O-][N+](=O)c1ccc(cc1)Nc1nc(nc(n1)N1CCOCC1)N1CCOCC1

InChi

InChI=1S/C17H21N7O4/c25-24(26)14-3-1-13(2-4-14)18-15-19-16(22-5-9-27-10-6-22)21-17(20-15)23-7-11-28-12-8-23/h1-4H,5-12H2,(H,18,19,20,21)

InChiKey

MSSXBKQZZINCRI-UHFFFAOYSA-N

MDL number

MFCD00489974

Technical guides

Understanding purity and quality - a guide for life scientists (159.4 KB)

References for MHY 1485

References are publications that support the biological activity of the product

MHY1485 enhances X-irradiation-induced apoptosis and senescence in tumor cells.
Sun L et al (2021) Journal of radiation research 62 : 782-792
Read more (PubMedID: 34265852)
MHY1485 activates mTOR and protects osteoblasts from dexamethasone.
Zhao S et al (2016) Biochemical and biophysical research communications 481 : 212-218
Read more (PubMedID: 27884298)
Inhibitory effect of mTOR activator MHY1485 on autophagy: suppression of lysosomal fusion.
Choi YJ et al (2012) PloS one 7 : e43418
Read more (PubMedID: 22927967)

mTOR activator and autophagy inhibitor. Cell-permeable.

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Order: HB7154
Pack	Price	Qty
10mg	$58
50mg	$182

MHY 1485

Product overview

Biological Data

Solubility & Handling

Calculators

Molarity

Dilution

Chemical Data

Technical guides

References for MHY 1485

MHY1485 enhances X-irradiation-induced apoptosis and senescence in tumor cells.

MHY1485 activates mTOR and protects osteoblasts from dexamethasone.

Inhibitory effect of mTOR activator MHY1485 on autophagy: suppression of lysosomal fusion.

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New Products in this Area

MHY 1485

Product overview

Biological Data

Solubility & Handling

Calculators

Molarity

Dilution

Chemical Data

Technical guides

References for MHY 1485

MHY1485 enhances X-irradiation-induced apoptosis and senescence in tumor cells.

MHY1485 activates mTOR and protects osteoblasts from dexamethasone.

Inhibitory effect of mTOR activator MHY1485 on autophagy: suppression of lysosomal fusion.

About you

Tell us about your publication!

Captcha

About you

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New Products in this Area

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