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Methyllycaconitine citrate (MLA)

(HB2026)
Publications (1)

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Product overview

Name Methyllycaconitine citrate (MLA)
Alternative names MLA
Purity >95%
Description Potent, selective α7 nicotinic receptor antagonist
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews Publications (1) Frequently bought together
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Biological Data

Biological description Potent and selective α7 nicotinic receptor antagonist (Ki = 1.4 nM). Shows protective effects against amyloid beta cytotoxicity. Active in vivo.

Solubility & Handling

Solubility overview Soluble in water (100 mM) and in DMSO (100 mM)
Storage instructions -20°C (desiccate)
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >95%
Chemical name [1α,4(S),6β,14α,16β]-20-Ethyl-1,6,14,16 -tetramethoxy-4-[[[2-(3-methyl-2,5-dioxo-1-pyrroli dinyl)benzoyl]oxy]methyl]aconitane-7,8-diol citrate
Molecular Weight 874.93
Chemical structure Methyllycaconitine citrate [112825-05-5] Chemical Structure
Molecular Formula C37H50N2O10.C6H8O7
CAS Number 112825-05-5
PubChem identifier 124081005
SMILES CCN1C[C@]2(CC[C@H]([C@@]34[C@@H]2[C@@H]([C@@]([C@@H]31)([C@@]5(C[C@@H]([C@H]6C[C@@H]4[C@@H]5[C@H]6OC)OC)O)O)OC)OC)COC(=O)C7=CC=CC=C7N8C(=O)C[C@H](C8=O)C.C(C(=O)O)C(CC(=O)O)(C(=O)O)O
Source Delphinium ajacis
InChi InChI=1S/C37H50N2O10.C6H8O7/c1-7-38-17-34(18-49-32(42)20-10-8-9-11-23(20)39-26(40)14-19(2)31(39)41)13-12-25(46-4)36-22-15-21-24(45-3)16-35(43,27(22)28(21)47-5)37(44,33(36)38)30(48-6)29(34)36;7-3(8)1-6(13,5(11)12)2-4(9)10/h8-11,19,21-22,24-25,27-30,33,43-4
InChiKey INBLZNJHDLEWPS-OXVGBIBJSA-N
MDL number MFCD00153837
Publications
Submit Yours Now
These publications cite the use of Methyllycaconitine citrate (MLA) purchased from Hello Bio:

  • Differential regulation of prelimbic and thalamic transmission to the basolateral amygdala by acetylcholine receptors

    Mott et al (2021) bioRxiv https://doi.org/10.1101/2021.12.28.474396 : doi

1 Item

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Grouped product items
Order: HB2026
Pack PriceQty
5mg
$73
25mg
$270
Potent, selective α7 nicotinic receptor antagonist
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

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