DNA methyltransferase (DNMT)

Potent, selective TGF-βRI inhibitor. Enhances cellular reprogramming efficiency.

Vesicular monoamine re-uptake blocker

Potent phenolic antioxidant with many biological actions. COX-1 inhibitor.

Topoisomerase I (Topo I) inhibitor.

Non-nucleoside DNA methyltransferase inhibitor. Enhances iPSC generation efficiency.

Na+ channel blocker / glutamate inhibitor. TREK-1 K2P channel activator.

Na⁺ channel blocker / glutamate inhibitor. TREK-1 K2P channel activator. Water soluble.

5-HT_2A and D₂ receptor antagonist

TRPV4 channel antagonist

Selective negative allosteric modulator of GluN2B (NR2B) containing NMDARs