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Reserpine

(HB1895)
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Product overview

Name Reserpine
Purity >99%
Description Vesicular monoamine re-uptake blocker
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (3) Frequently bought together
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Biological Data

Biological description Vesicular monoamine re-uptake blocker. Irreversibly binds VMAT2 to deplete synaptic monoamines. Produces depression-like effects and shows antipsychotic and antihypertensive effects.

Solubility & Handling

Solubility overview Soluble in DMSO (10 mM)
Storage instructions Room temperature
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >99%
Chemical name (3β,16β,17α,18β,20α)-11,17-Dimethoxy-18- [(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxyl ic acid methyl ester
Molecular Weight 608.68
Chemical structure Reserpine [50-55-5] Chemical Structure
Molecular Formula C33H40N2O9
CAS Number 50-55-5
PubChem identifier 5770
SMILES CO[C@H]1[C@@H](C[C@@H]2CN3CCC4=C([C@H]3C[C@@H]2[C@@H]1C(=O)OC)NC5=C4C=CC(=C5)OC)OC(=O)C6=CC(=C(C(=C6)OC)OC)OC
InChi InChI=1S/C33H40N2O9/c1-38-19-7-8-20-21-9-10-35-16-18-13-27(44-32(36)17-11-25(39-2)30(41-4)26(12-17)40-3)31(42-5)28(33(37)43-6)22(18)15-24(35)29(21)34-23(20)14-19/h7-8,11-12,14,18,22,24,27-28,31,34H,9-10,13,15-16H2,1-6H3/t18-,22+,24-,27-,28+,31+/m1/s1
InChiKey QEVHRUUCFGRFIF-MDEJGZGSSA-N
MDL number MFCD00005091

References for Reserpine

References are publications that support the biological activity of the product

  • Antidepressant-like effect of tetrahydroisoquinoline amines in the animal model of depressive disorder induced by repeated administration of a low dose of reserpine: behavioral and neurochemical studies in the rat.

    Antkiewicz-Michaluk L et al (2014) Neurotox Res 26(1) : 85-98.
    Read more (PubMedID: 24407488)

  • Reserpine binding to a vesicular amine transporter expressed in Chinese hamster ovary fibroblasts.

    Schuldiner S et al (1993) J Biol Chem 268(1) : 29-34.
    Read more (PubMedID: 8416935)

  • Radioligands of the vesicular monoamine transporter and their use as markers of monoamine storage vesicles.

    Henry JP et al (1989) Biochem Pharmacol 38(15) : 2395-404.
    Read more (PubMedID: 2667522)

3 Item(s)

Grouped product items
Order: HB1895
Pack PriceQty
1g
$101
Vesicular monoamine re-uptake blocker
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

Shipping will be calculated at checkout

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