Product overview

Name Reserpine
Purity >99%
Description Vesicular monoamine re-uptake blocker
Write Your Own Review
You're reviewing:Reserpine
Rate this item:

Biological Data

Biological description Vesicular monoamine re-uptake blocker. Irreversibly binds VMAT2 to deplete synaptic monoamines. Produces depression-like effects and shows antipsychotic and antihypertensive effects.

Solubility & Handling

Storage instructions Room temperature
Solubility overview Soluble in DMSO (10 mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

=
x
x
More Info

Dilution

x
=
x
More Info

Chemical Data

Purity >99%
Chemical name (3β,16β,17α,18β,20α)-11,17-Dimethoxy-18- [(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxyl ic acid methyl ester
Molecular Weight 608.68
Chemical structure Reserpine  [50-55-5] Chemical Structure
Molecular Formula C33H40N2O9
CAS Number 50-55-5
PubChem identifier 5770
SMILES CO[C@H]1[C@@H](C[C@@H]2CN3CCC4=C([C@H]3C[C@@H]2[C@@H]1C(=O)OC)NC5=C4C=CC(=C5)OC)OC(=O)C6=CC(=C(C(=C6)OC)OC)OC
InChi InChI=1S/C33H40N2O9/c1-38-19-7-8-20-21-9-10-35-16-18-13-27(44-32(36)17-11-25(39-2)30(41-4)26(12-17)40-3)31(42-5)28(33(37)43-6)22(18)15-24(35)29(21)34-23(20)14-19/h7-8,11-12,14,18,22,24,27-28,31,34H,9-10,13,15-16H2,1-6H3/t18-,22+,24-,27-,28+,31+/m1/s1
InChiKey QEVHRUUCFGRFIF-MDEJGZGSSA-N
MDL number MFCD00005091

References for Reserpine

References are publications that support the biological activity of the product
  • Antidepressant-like effect of tetrahydroisoquinoline amines in the animal model of depressive disorder induced by repeated administration of a low dose of reserpine: behavioral and neurochemical studies in the rat.

    Antkiewicz-Michaluk L et al (2014) Neurotox Res 26(1) : 85-98.
  • Reserpine binding to a vesicular amine transporter expressed in Chinese hamster ovary fibroblasts.

    Schuldiner S et al (1993) J Biol Chem 268(1) : 29-34.
  • Radioligands of the vesicular monoamine transporter and their use as markers of monoamine storage vesicles.

    Henry JP et al (1989) Biochem Pharmacol 38(15) : 2395-404.

3 Item(s)