Kinase
Protein kinases (phosphotransferases) are enzymes that catalyze phosphorylation. They phosphorylate specific amino acids using ATP as the source of phosphate. In this way, the biological activity of proteins is regulated; phosphorylation induces a conformational change from an inactive to an active form of the protein. Researchers can save up to 50% on kinase inhibitors and activators from Hello Bio - they are up to half the price of other suppliers.Â
View products: Akt / PKB | AMPK | Aurora kinase | BTK | CAM Kinase II | Casein kinase | CDK | c-Src | DYRK | ERK | GRK | GSK-3 | Hexokinase | JAK | MAPK | mTOR | Myosin light chain kinase (MLCK) | Non-selective | PKA | PKC | PKG | PI-3K | Protein-serine/threonine kinase | Protein-tyrosine kinase | RIP | ROCK | RSK| Sphingosine kinase | Syk |Raf | View Resources: Enzyme Inhibitors & Activators
Cyclosporin A (HB0220)
Description:Potent calcineurin inhibitor. Inhibits MPTP opening.
Purity:>99%
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Dexamethasone (HB2521)
Description:Anti-inflammatory synthetic glucocorticoid. Induces hMSC differentiation. Apoptosis inducer.
Purity:>98%
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Dexamethasone (water-soluble) (HB6020)
Description:Synthetic glucocorticoid with potent anti-inflammatory actions. Induces hMSC differentiation. Apoptosis inducer. Water soluble and suitable for cell culture.Â
Purity:>98%
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FK 506 (HB0289)
Description:Potent calcineurin phosphatase 2B inhibitor. Enhances osteoblastic differentiation in mesenchymal cells.
Purity:>99%
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FTY720 hydrochloride (HB3899)
Description:Sphingosine 1-phosphate (S1P) receptor (S1P1, S1P3, S1P4, and S1P5) modulator
Purity:>98%
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Mycophenolic acid (HB3987)
Description:Inosine monophosphatase dehydrogenase inhibitor
Purity:>98%
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Rapamycin (HB2779)
Description:mTOR inhibitor and potent immunosuppressant. Also used in inducible gene editing methods (e.g. CRISPR/Cas9) and promotes hPSC differentiation.
Purity:>98%
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6-Thioguanine (HB1379)
Description:Competitive hypoxanthine-guanine phosphoribosyltransferase substrate
Purity:>99%
