Cell permeable immunosuppressor which displays lymphocyte sequestration properties. It is a sphingosine 1-phosphate (S1P) receptor modulator (S1P1, S1P3, S1P4, and S1P5) when phosphorylated by sphingosine kinase.
It also enhances activity of Sphingosine transporter Abcb1 and leukotriene C4 transporter Abcc1 and inhibits Cytosolic phospholipase A2 independent of sphingosine 1-phosphate receptors.
It induces autophagy and apoptosis and shows immunosuppresant actions. Also suppresses the development of the multiple sclreosis EAE model.
Recently investigated as part of COVID-19 compound repurposing.
Solubility & Handling
Solubility overview
Soluble in DMSO
Storage instructions
+4°C
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
![FTY720 hydrochloride [162359-56-0] Chemical Structure](https://cdn.hellobio.com/media/catalog/product//h/b/hb3899.png "FTY720 hydrochloride [162359-56-0]")
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