Product overview

Name FTY720 hydrochloride
Alternative names Fingolimod
Purity >98%
Description Sphingosine 1-phosphate (S1P) receptor (S1P1, S1P3, S1P4, and S1P5) modulator
Write Your Own Review
You're reviewing:FTY720 hydrochloride
Rate this item:

Biological Data

Biological description

Cell permeable immunosuppressor which displays lymphocyte sequestration properties. It is a sphingosine 1-phosphate (S1P) receptor modulator (S1P1, S1P3, S1P4, and S1P5) when phosphorylated by sphingosine kinase.

It also enhances activity of Sphingosine transporter Abcb1 and leukotriene C4 transporter Abcc1 and inhibits Cytosolic phospholipase A2 independent of sphingosine 1-phosphate receptors.

It induces autophagy and apoptosis and shows immunosuppresant actions. Also suppresses the development of the multiple sclreosis EAE model.

Recently investigated as part of COVID-19 compound repurposing.

Solubility & Handling

Storage instructions +4°C
Solubility overview Soluble in DMSO
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

=
x
x
More Info

Dilution

x
=
x
More Info

Chemical Data

Purity >98%
Chemical name 2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol Hydrochloride
Molecular Weight 343.9
Chemical structure FTY720 hydrochloride [162359-56-0] Chemical Structure
Molecular Formula C19H33NO2.HCl
CAS Number 162359-56-0
SMILES [H+].[Cl-].CCCCCCCCc1ccc(CCC(N)(CO)CO)cc1
InChiKey SWZTYAVBMYWFGS-UHFFFAOYSA-N
Appearance White solid