Product overview

Name IDR 1002
Biological description

Innate defence regulator peptide which enhances chemokine production and neutrophil and monocyte recruitment to protect against bacterial infections. Shows antimicrobial, immunomodulatory and anti-inflammatory properties.

Purity >95%
Description

Innate defence regulator peptide

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Solubility & Handling

Storage instructions -20°C
Solubility overview

Soluble in aqueous buffer

Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

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Dilution

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Chemical Data

Purity >95%
Molecular Weight 1652.06
Molecular Formula C79H130N26O13
Sequence (one letter) VQRWLIVWRIRK-NH2
Sequence (three letter) H-Val-Gln-Arg-Trp-Leu-Ile-Val-Trp-Arg-Ile-Arg-Lys-NH2
CAS Number 1224095-25-3

References for IDR 1002

References are publications that support the biological activity of the product
  • Synthetic host defense peptide IDR-1002 reduces inflammation in Pseudomonas aeruginosa lung infection

    Wuerth KC et al (2017) PLoS One 12(11) : e0187565
  • Synthetic immunomodulatory peptide IDR-1002 enhances monocyte migration and adhesion on fibronectin

    Madera L et al (2012) J Innate Immun 4(5-6) : 553-68
  • Synthetic cationic peptide IDR-1002 provides protection against bacterial infections through chemokine induction and enhanced leukocyte recruitment

    Nijnik A et al (2010) J Immunol 184(5) : 2539-50

3 Item(s)