Antibiotic which is a potent, reversible inosine monophosphatase dehydrogenase inhibitor. It is 5-fold more potent at type II compared to type I isoforms.
It is also an iNOS inhibitor and additionally inhibits RNA and DNA synthesis. It shows immunosuppressive, antiviral, antifungal and antitumor properties andinduces apoptosis and necrosis.
Recently investigated as part of COVID-19 compound repurposing.
Solubility & Handling
Solubility overview
Soluble in DMSO (100 mM)
Storage instructions
Room temperature
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.