Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  2. Description:

    Serine protease inhibitor. Inhibits TMPRSS2 and partially blocks SARS-Cov2 entry in vitro.

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    >98%

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  5. Cycloheximide (HB2904)

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    Eukaryotic protein synthesis inhibitor. Apoptosis inducer.

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    >95%

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  6. Cyclosporin A (HB0220)

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    Potent calcineurin inhibitor. Inhibits MPTP opening.

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    >99%

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    RNA and DNA synthesis inhibitor. Antibiotic.

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    >98%

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  8. Dexamethasone (HB2521)

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    Anti-inflammatory synthetic glucocorticoid. Induces hMSC differentiation. Apoptosis inducer.

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    >98%

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    Description:

    Synthetic glucocorticoid with potent anti-inflammatory actions. Induces hMSC differentiation. Apoptosis inducer. Water soluble and suitable for cell culture. 

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    >98%

    Pack:
    100mg
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    $109
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