Widely-used eukaryotic protein synthesis inhibitor. Blocks the elongation phase of translation by binding to the E-site of the 60S ribosomal subunit to block eEF2-mediated tRNA translocation.
Induces apoptosis in various cells but can also delay or inhibit apoptosis.
Also inhibits FKBP12 and shows potent antifungal and anti-mold activity.
Solubility & Handling
Solubility overview
Soluble in ethanol (50 mM) and water (25 mM)
Storage instructions
room temperature
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Understanding purity and quality - a guide for life scientists