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Chloroquine diphosphate

(HB5073)
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Product overview

Name Chloroquine diphosphate
Description Antimalarial. Apoptosis and autophagy inhibitor.
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (3) Frequently bought together
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Biological Data

Biological description

Antimalarial compound with various biological actions (anti-inflammatory, immunomodulatory, antiviral, anticancer etc.). It inhibits cell growth, proliferation and viability and also induces apoptosis and autophagy.

It inhibits viral replication to show antiviral activity and inhibits SARS-CoV-2 viral infection (COVID-19) in vitro.

Solubility & Handling

Storage instructions

Room temperature (desiccate)

Solubility overview Soluble in water (100mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

Molarity

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More Info

Dilution

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More Info

Chemical Data

Chemical name N4-(7-Chloro-4-quinolinyl)-N1,N1-dimethyl-1,4-pentanediamine diphosphate salt
Molecular Weight 515.86
Chemical structure Chemical Structure
Molecular Formula C18H26ClN3?2H3PO4
CAS Number 50-63-5
PubChem identifier 64927
SMILES CCN(CC)CCCC(C)NC2=CC=NC1=CC(Cl)=CC=C12.O=P(O)(O)O.O=P(O)(O)O
InChi InChI=1S/C18H26ClN3.2H3O4P/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18;2*1-5(2,3)4/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21);2*(H3,1,2,3,4)
InChiKey QKICWELGRMTQCR-UHFFFAOYSA-N
MDL number MFCD00069852

References for Chloroquine diphosphate

References are publications that support the biological activity of the product

  • Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro

    Wang M et al (2020) Cell Res 30(3) : 269-271
    Read more (PubMedID: 32020029)

  • Chloroquine potentiates the anti-cancer effect of 5-fluorouracil on colon cancer cells

    Sasaki K et al (2010) BMC Cancer 10 : 370
    Read more (PubMedID: 20630104)

  • Effect of chloroquine on human lymphocyte proliferation

    Bygbjerg IC et al (1986) Trans R Soc Trop Med Hyg 80(2) : 231-5
    Read more (PubMedID: 3787684)

3 Item(s)

Related Products
Grouped product items
Order: HB5073
Pack PriceQty
1g
$33
5g
$97
10g
$174
Antimalarial. Apoptosis and autophagy inhibitor.
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

Shipping will be calculated at checkout

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