Product overview

Name Chloroquine diphosphate
Description Antimalarial. Apoptosis and autophagy inhibitor.
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Biological Data

Biological description

Antimalarial compound with various biological actions (anti-inflammatory, immunomodulatory, antiviral, anticancer etc.). It inhibits cell growth, proliferation and viability and also induces apoptosis and autophagy.

It inhibits viral replication to show antiviral activity and inhibits SARS-CoV-2 viral infection (COVID-19) in vitro.

Solubility & Handling

Storage instructions RT (desiccate)
Solubility overview Soluble in water (100mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

Molarity

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Dilution

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References for Chloroquine diphosphate

References are publications that support the biological activity of the product
  • Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro

    Wang M et al (2020) Cell Res 30(3) : 269-271
  • Chloroquine potentiates the anti-cancer effect of 5-fluorouracil on colon cancer cells

    Sasaki K et al (2010) BMC Cancer 10 : 370
  • Effect of chloroquine on human lymphocyte proliferation

    Bygbjerg IC et al (1986) Trans R Soc Trop Med Hyg 80(2) : 231-5