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Camostat mesylate

(HB3595)
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Product overview

Name Camostat mesylate
Purity >98%
Description Serine protease inhibitor. Inhibits TMPRSS2 and partially blocks SARS-Cov2 entry in vitro.
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (3) Frequently bought together
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Biological Data

Biological description

Serine protease inhibitor. Orally active.

Show various biological actions including antiviral, anticancer and suppresses pancreatitis-induced pain in rats.

Inhibits the transmembrane protease TMPRSS2 and partially blocks entry of SARS-Cov-2 into lung cells in vitro.

Solubility & Handling

Solubility overview Soluble in water (100mM) and in DMSO (100mM)
Storage instructions

Room temperature (desiccate)

Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

Molarity

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Dilution

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Chemical Data

Purity >98%
Chemical name 4-[[4-[(Aminoiminomethyl)amino]benzoyl]oxy]benzeneacetic acid 2-(dimethylamino)-2-oxoethyl ester methanesulfonate
Molecular Weight 494.52
Chemical structure Camostat mesylate [59721-29-8] Chemical Structure
Molecular Formula C20H22N4O5.CH3SO3H
CAS Number 59721-29-8
PubChem identifier 43071
SMILES O=C(C2=CC=C(NC(N)=N)C=C2)OC1=CC=C(CC(OCC(N(C)C)=O)=O)C=C1.CS(=O)(O)=O
InChi InChI=1S/C20H22N4O5.CH4O3S/c1-24(2)17(25)12-28-18(26)11-13-3-9-16(10-4-13)29-19(27)14-5-7-15(8-6-14)23-20(21)22;1-5(2,3)4/h3-10H,11-12H2,1-2H3,(H4,21,22,23);1H3,(H,2,3,4)
InChiKey FSEKIHNIDBATFG-UHFFFAOYSA-N
MDL number MFCD00941410

References for Camostat mesylate

References are publications that support the biological activity of the product

  • SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

    Hoffmann et al (2020) Cell. 181(2) : 271-380
    Read more (PubMedID: 32142651)

  • Camostat mesilate inhibits prostasin activity and reduces blood pressure and renal injury in salt-sensitive hypertension

    Maekawa et al (2009) J Hypertens. 27(1) : 181-9
    Read more (PubMedID: 19145783)

  • The proteinase inhibitor camostat mesilate suppresses pancreatic pain in rodent

    Ishikura et al (2007) Life Sci. 80(21) : 1999-2004
    Read more (PubMedID: 17433371)

3 Item(s)

Related Products
Grouped product items
Order: HB3595
Pack PriceQty
10mg
$42
50mg
$154
Serine protease inhibitor. Inhibits TMPRSS2 and partially blocks SARS-Cov2 entry in vitro.
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

Shipping will be calculated at checkout

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