Product overview

Name Camostat mesylate
Purity >98%
Description Serine protease inhibitor. Inhibits TMPRSS2 and partially blocks SARS-Cov2 entry in vitro.
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Biological Data

Biological description

Serine protease inhibitor. Orally active.

Show various biological actions including antiviral, anticancer and suppresses pancreatitis-induced pain in rats.

Inhibits the transmembrane protease TMPRSS2 and partially blocks entry of SARS-Cov-2 into lung cells in vitro.

Solubility & Handling

Storage instructions

Room temperature (desiccate)

Solubility overview Soluble in water (100mM) and in DMSO (100mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use



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Chemical Data

Purity >98%
Chemical name 4-[[4-[(Aminoiminomethyl)amino]benzoyl]oxy]benzeneacetic acid 2-(dimethylamino)-2-oxoethyl ester methanesulfonate
Molecular Weight 494.52
Chemical structure Camostat mesylate [59721-29-8] Chemical Structure
Molecular Formula C20H22N4O5.CH3SO3H
CAS Number 59721-29-8
PubChem identifier 43071
InChi InChI=1S/C20H22N4O5.CH4O3S/c1-24(2)17(25)12-28-18(26)11-13-3-9-16(10-4-13)29-19(27)14-5-7-15(8-6-14)23-20(21)22;1-5(2,3)4/h3-10H,11-12H2,1-2H3,(H4,21,22,23);1H3,(H,2,3,4)
MDL number MFCD00941410

References for Camostat mesylate

References are publications that support the biological activity of the product
  • SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

    Hoffmann et al (2020) Cell. 181(2) : 271-380
  • Camostat mesilate inhibits prostasin activity and reduces blood pressure and renal injury in salt-sensitive hypertension

    Maekawa et al (2009) J Hypertens. 27(1) : 181-9
  • The proteinase inhibitor camostat mesilate suppresses pancreatic pain in rodent

    Ishikura et al (2007) Life Sci. 80(21) : 1999-2004

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