Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. Description:

    Estrogen receptor antagonist/ partial agonist. May be used in genome engineering (e.g. CreER/ CRISPR-Cas9). Citrate salt.

    Purity:

    >98%

    Pack:
    500mg
    Price:
    $74
    Qty:
    Pack:
    1g
    Price:
    $126
    Qty:
    Pack:
    5g
    Price:
    $508
    Qty:
  2. Pack:
    10mg
    Price:
    $42
    Qty:
    Pack:
    50mg
    Price:
    $106
    Qty:
  3. Torin 1 (HB2253)

    Description:

    Potent, selective mTOR inhibitor

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $160
    Qty:
    Pack:
    50mg
    Price:
    $466
    Qty:
  4. Torin 2 (HB2254)

    Description:

    Potent, selective mTOR inhibitor

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $462
    Qty:
  5. Pack:
    1mg
    Price:
    Qty:
    Pack:
    5mg
    Price:
    $171
    Qty:
    Pack:
    25mg
    Price:
    $708
    Qty:
  6. Description:

    Histone deacetylase inhibitor. Shows multitude of biological actions. Enables pluripotent stem cell induction from somatic cells.

    Pack:
    10g
    Price:
    $53
    Qty:
  7. Pack:
    5mg
    Price:
    $48
    Qty:
    Pack:
    10mg
    Price:
    $76
    Qty:
    Pack:
    25mg
    Price:
    $176
    Qty:
    Pack:
    50mg
    Price:
    $326
    Qty:
  8. Pack:
    1g
    Price:
    $75
    Qty:
    Pack:
    50mM (add 1ml water)
    Price:
    $42
    Qty:
  9. Viridiol (HB4121)

    Description:

    PI3K inhibitor

    Purity:

    >95%

    Pack:
    250μg
    Price:
    $75
    Qty:
    Pack:
    1mg
    Price:
    $213
    Qty:
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