Product overview

Name TFLLR-NH2
Biological description TFLLR-NH2 is a selective PAR1 (protease-activated receptor-1) activating peptide. It is commonly used to activate platelets and has also been shown to elicit scratching in mice. Active in vivo.
Alternative names TFLLR, TF-NH2
Purity >95%
Description Selective PAR1 activating peptide
Write Your Own Review
You're reviewing:TFLLR-NH2
Rate this item:

Solubility & Handling

Storage instructions -20°C
Solubility overview Soluble in water (1 mg/ml)
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

Molarity

=
x
x
More Info

Dilution

x
=
x
More Info

Chemical Data

Purity >95%
Chemical name TFLLR (modifications: C-terminal amide)
Molecular Weight 647.82
Chemical structure TFLLR-NH2 | [197794-83-5] Chemical Structure
Molecular Formula C76H104N18O19S2
Sequence (one letter) TFLLR
Modifications C-terminal amide
CAS Number 197794-83-5
PubChem identifier 10146183
SMILES C[C@H]([C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N)N)O
InChiKey ANAMCEKSRDPIPX-GFGQVAFXSA-N
MDL number MFCD05663482

References for TFLLR-NH2

References are publications that support the biological activity of the product
  • Activation of platelet protease-activated receptor-1 induces epithelial-mesenchymal transition and chemotaxis of colon cancer cell line SW620.

    Jia et al (26718652) Oncol Rep 35(2) : 1222
  • Activation of proteinase-activated receptors induces itch-associated response through histamine-dependent and -independent pathways in mice.

    Tsujii et al (2008) J Pharmacol Sci. 108(3) : 385-8
  • A role for proteinase-activated receptor-1 in inflammatory bowel diseases.

    Vergnolle et al (2004) J Clin Ivest. 114(10) : 1444-56

3 Item(s)