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Solubility & Handling Storage instructions -20°C
Solubility overview Soluble in water (1 mg/ml)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use
Chemical Data Chemical name TFLLR (modifications: C-terminal amide)
Chemical structure
Molecular Formula C76 H104 N18 O19 S2
Sequence (one letter) TFLLR
Modifications C-terminal amide
PubChem identifier 10146183
SMILES C[C@H]([C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N)N)O
InChiKey ANAMCEKSRDPIPX-GFGQVAFXSA-N
References for TFLLR-NH2 References are publications that support the biological activity of the product
Activation of platelet protease-activated receptor-1 induces epithelial-mesenchymal transition and chemotaxis of colon cancer cell line SW620. Jia et al (26718652) Oncol Rep 35(2) : 1222
Activation of proteinase-activated receptors induces itch-associated response through histamine-dependent and -independent pathways in mice. Tsujii et al (2008) J Pharmacol Sci. 108(3) : 385-8 A role for proteinase-activated receptor-1 in inflammatory bowel diseases. Vergnolle et al (2004) J Clin Ivest. 114(10) : 1444-56
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Selective PAR1 activating peptide