Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. Description:

    Protein synthesis inhibitor. Cell culture selection antibiotic.

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $49
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  2. Rapamycin (HB2779)

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    Description:

    mTOR inhibitor and potent immunosuppressant. Also used in inducible gene editing methods (e.g. CRISPR/Cas9) and promotes hPSC differentiation.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $146
    Free trial
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    Pack:
    5mg
    Price:
    $247
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  3. Remdesivir (HB9521)

    Description:

    Adenosine triphosphate analog with broad-spectrum antiviral activity

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $47
    Qty:
    Pack:
    10mg
    Price:
    $107
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    Pack:
    50mg
    Price:
    $433
    Qty:
  4. Pack:
    50mg
    Price:
    $36
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    Pack:
    250mg
    Price:
    $111
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    Pack:
    1g
    Price:
    $323
    Qty:
  5. Pack:
    10mg
    Price:
    $36
    Qty:
    Pack:
    50mg
    Price:
    $108
    Qty:
  6. RS-1 (HB5647)

    Description:

    hRAD51 stimulator. Enhances CRISPR genome editing efficiency.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    Qty:
    Pack:
    50mg
    Price:
    $278
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  7. RWJ 67657 (HB1300)

    Description:

    Potent p38 MAPK inhibitor

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $52
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    Pack:
    5mg
    Price:
    $88
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    Pack:
    10mg
    Price:
    $162
    Qty:
  8. S14161 (HB4068)

    Description:

    pan Class I PI3K isoforms inhibitor

    Purity:

    >99%

    Pack:
    5mg
    Price:
    $367
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  9. SB 202190 (HB1301)

    Description:

    Potent ATP competitive p38 MAPK inhibitor. 3D growth matrix component, promotes long-term organoid growth and can be used in production of gastric organoids. Promotes stability of human pluripotent stem cells.

    Purity:

    >99%

    Pack:
    5mg
    Price:
    Qty:
    Pack:
    10mg
    Price:
    $137
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    Pack:
    25mg
    Price:
    $339
    Qty:
    Pack:
    50mg
    Price:
    $570
    Qty:
  10. SB 203580 (HB1302)

    Description:

    Potent, selective p38 MAPK inhibitor. Stimulates neural stem cell proliferation.

    Purity:

    >98%

    Pack:
    500μg
    Price:
    $47
    Qty:
    Pack:
    1mg
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    Pack:
    10mg
    Price:
    $191
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    Pack:
    50mg
    Price:
    $703
    Qty:
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