Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. Pack:
    10mg
    Price:
    $270
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    50mg
    Price:
    $1,068
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    5mg
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    $109
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  3. Pack:
    5mg
    Price:
    $97
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  4. 4  Reviews
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    Description:

    Selective GluA2- lacking, Ca2+ permeable AMPA / kainate receptor antagonist

    Purity:

    >95%

    Pack:
    5mg
    Price:
    $74
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    Pack:
    10mg
    Price:
    $122
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    25mg
    Price:
    $240
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    50mg
    Price:
    $438
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  5. NBQX (HB0442)

    2  Reviews
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    Description:

    Potent, selective, competitive AMPA receptor antagonist

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $173
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    Pack:
    50mg
    Price:
    $726
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  6. 30  Reviews
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    Description:

    Potent, selective, competitive AMPA receptor antagonist. Disodium salt.

    Purity:

    >99%

    Pack:
    1mg
    Price:
    $93
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    Pack:
    10mg
    Price:
    $193
    Free trial
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    Pack:
    50mg
    Price:
    $816
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    Pack:
    50mM (add 1ml water)
    Price:
    $460
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    Pack:
    100mM (add 1ml water)
    Price:
    $801
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  7. Necrostatin-5 (HB3994)

    Description:

    Necroptosis inhibitor. Indirect RIP1 kinase inhibitor.

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $229
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  8. Necrostatin-7 (HB3995)

    Description:

    Necroptosis inhibitor. Shows no action at RIP1 kinase.

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $401
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  9. Description:

    Antibody to NeuN - marker for mature neurones expressed in the nucleus. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Rabbit
    Clonality: Polyclonal
    Reactivity Tested: Mouse, Rat
    Pack:
    25μg
    Price:
    $153
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    Pack:
    100μg
    Price:
    $372
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