Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. Description:

    Antibody to Ki-67 - a widely used marker of proliferating cells. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Human
    Pack:
    25μg
    Price:
    $139
    Qty:
    Pack:
    100μg
    Price:
    $310
    Qty:
  2. Kirromycin (HB3951)

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    Description:

    Antibacterial antibiotic and protein synthesis inhibitor

    Purity:

    >96%

    Pack:
    1mg
    Price:
    $209
    Qty:
    Pack:
    5mg
    Price:
    $619
    Qty:
  3. Pack:
    1mg
    Price:
    $143
    Qty:
  4. Pack:
    100μg
    Price:
    $157
    Qty:
  5. KT 5823 (HB1316)

    Description:

    Potent, selective PKG inhibitor

    Purity:

    >98%

    Pack:
    50μg
    Price:
    $127
    Qty:
    Pack:
    250μg
    Price:
    $502
    Qty:
  6. KU 0063794 (HB2250)

    Description:

    Potent, selective mTOR inhibitor

    Purity:

    >97%

    Pack:
    10mg
    Price:
    $259
    Qty:
    Pack:
    50mg
    Price:
    $1,047
    Qty:
  7. KY 02111 (HB3465)

    Description:

    Wnt signaling inhibitor. Promotes differentiation of hESCs and iPSCs into cardiomyocytes.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $163
    Qty:
    Pack:
    50mg
    Price:
    $595
    Qty:
  8. Pack:
    250mg
    Price:
    $35
    Qty:
    Pack:
    1g
    Price:
    $54
    Qty:
    Pack:
    5g
    Price:
    $158
    Qty:
  9. Pack:
    1g
    Price:
    $108
    Qty:
    Pack:
    5g
    Price:
    $367
    Qty:
    Pack:
    100mM (add 1ml water)
    Price:
    $45
    Qty:
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