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KN-93 phosphate (water soluble)

(HB0360)
Publications (2)
Technical documents: SDS Datasheet
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Product overview

Name KN-93 phosphate (water soluble)
Purity >98%
Description Potent CaM kinase II inhibitor
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews Publications (2) Frequently bought together
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KN-93 phosphate (water soluble) product vial image | Hello Bio
KN-93 phosphate (water soluble) product vial image | Hello Bio

KN-93 phosphate (water soluble) product vial image | Hello Bio

KN-93 phosphate (water soluble) product vial image | Hello Bio

Biological Data

Biological description Potent CaM kinase II inhibitor (IC50 = 0.37 µM). Also acts as a direct, extracellular voltage-gated K+ channels blocker (IC50 = 307 nM at Kv1.5 channels) in a manner which is independent of CaMKII. KN-93 may act via promotion and stabilization of C-type inactivation.

Solubility & Handling

Storage instructions +4°C
Solubility overview Soluble in water
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >98%
Chemical name N-[2-[[[3-(4-Chlorophenyl)-2-propenyl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4 -methoxybenzenesulphonamide phosphate
Molecular Weight 501
Chemical structure KN-93 [1188890-41-6] Chemical Structure
Molecular Formula C26H29ClN2O4S.H33PO4
CAS Number 1188890-41-6
PubChem identifier 16760530
SMILES CN(CC=CC1=CC=C(C=C1)Cl)CC2=CC=CC=C2N(CCO)S(=O)(=O)C3=CC=C(C=C3)OC
InChiKey LLLQTDSSHZREGW-AATRIKPKSA-N
Publications
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These publications cite the use of KN-93 phosphate (water soluble) purchased from Hello Bio:

  • Impaired State-Dependent Potentiation of GABAergic Synaptic Currents Triggers Seizures in a Genetic Generalized Epilepsy Model

    Zhang CQ et al (2021) Cereb Cortex 31(2) : 768-784
    PubMedID: 32930324

  • Impaired state-dependent potentiation of GABAergic synaptic currents triggers seizures in an idiopathic generalized epilepsy model

    Zhou et al (2020) bioRxiv https://doi.org/10.1101/2020.05.10.087114 : doi

2 Item(s)

Grouped product items
Order: HB0360
Pack PriceQty
1mg
$191
Potent CaM kinase II inhibitor
Shipping Info

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Hazardous: $35

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