Product overview

Name KU 0063794
Description Potent, selective mTOR inhibitor
Purity >97%
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Biological Data

Biological description Potent and selective mTOR inhibitor (IC50 = ~10 nM at mTORC1 and mTORC2). Shows little actvity at 76 other protein kinases or 7 lipid kinases. Cell permeable. Supresses cell viability and growth and by inducing cell cycle arrest and autophagy.

Solubility & Handling

Storage instructions Room temperature
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Chemical Data

Chemical name rel-5-[2-[(2R,6S)-2,6-dimethyl-4-mo rpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin -7-yl]-2-methoxybenzenemethanol
Molecular Weight 465.54
Molecular Formula C25H31N5O4
CAS Number 938440-64-3
PubChem identifier 16736978
SMILES OCC1=C(OC)C=CC(C3=NC2=NC(N5C[C@@H](C)O[C@@H](C)C5)=NC(N4CCOCC4)=C2C=C3)=C1
InChiKey RFSMUFRPPYDYRD-CALCHBBNSA-N