Product overview
| Name | KU 0063794 |
| Description | Potent, selective mTOR inhibitor |
| Purity | >97% |
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Biological Data
| Biological description | Potent and selective mTOR inhibitor (IC50 = ~10 nM at mTORC1 and mTORC2). Shows little actvity at 76 other protein kinases or 7 lipid kinases. Cell permeable. Supresses cell viability and growth and by inducing cell cycle arrest and autophagy. |
Solubility & Handling
| Storage instructions | Room temperature |
| Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
| Chemical name | rel-5-[2-[(2R,6S)-2,6-dimethyl-4-mo rpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin -7-yl]-2-methoxybenzenemethanol |
| Molecular Weight | 465.54 |
| Molecular Formula | C25H31N5O4 |
| CAS Number | 938440-64-3 |
| PubChem identifier | 16736978 |
| SMILES | OCC1=C(OC)C=CC(C3=NC2=NC(N5C[C@@H](C)O[C@@H](C)C5)=NC(N4CCOCC4)=C2C=C3)=C1 |
| InChiKey | RFSMUFRPPYDYRD-CALCHBBNSA-N |
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