Potent and selective mTOR inhibitor (IC50 = ~10 nM at mTORC1 and mTORC2). Shows little actvity at 76 other protein kinases or 7 lipid kinases. Cell permeable. Supresses cell viability and growth and by inducing cell cycle arrest and autophagy.
Solubility & Handling
Storage instructions
Room temperature
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Understanding purity and quality - a guide for life scientists