Product overview

Name Compound E
Purity >98%
Description Potent, selective, non-competitive γ-secretase inhibitor. Induces neuronal differentiation.
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Biological Data

Biological description

Cell permeable, potent, selective, non-transition state and non-competitive gamma-secretase inhibitor. Notch processing inhibitor. Only weakly affects presenilinase activity.

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Solubility & Handling

Storage instructions +4°C
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

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Dilution

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Chemical Data

Purity >98%
Chemical name (2S)-2-([(3,5-Difluorophenyl)acetyl]amino)-N-[(3S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]propanamide
Molecular Weight 490.5
Chemical structure Compound E [209986-17-4] Chemical Structure
Molecular Formula C27H24F2N4O3
CAS Number 209986-17-4
PubChem identifier 11306390
SMILES C[C@@H](C(N[C@H]1N=C(C2=CC=CC=C2N(C1=O)C)C3=CC=CC=C3)=O)NC(CC4=CC(F)=CC(F)=C4)=O
InChiKey JNGZXGGOCLZBFB-IVCQMTBJSA-N
Appearance White to off-white solid