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Cyclopamine

(HB2965)
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Product overview

Name Cyclopamine
Purity >98%
Description Smo and hedgehog (Hh) signaling inhibitor. Also depletes stem like cancer cells and induces hESCs into endocrine cells.
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (2) Reviews Frequently bought together
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Biological Data

Biological description Smo Inhibitor and hedgehog (Hh) signaling inhibitor. Depletes stem like cancer cells and induces hESCs into endocrine cells. Blocks abnormal cell growth associated with fibroblast Ptch and Smo oncogenic mutations. Also induces apoptosis and arrests cell cycle at G0/G1 phase and depletes stem like cancer cells. Shows anticancer activity.

Solubility & Handling

Storage instructions +4°C
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >98%
Chemical name (2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,11bR)-1,2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11,11a,11b-Octadecahydro-3',6',10,11b-tetramethylspiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-3-ol
Molecular Weight 411.6
Chemical structure Cyclopamine | 11-Deoxyjervine | 11-Deoxojervine | HSDB 3505 [4449-51-8] Chemical Structure
Molecular Formula C27H41NO2
CAS Number 4449-51-8
PubChem identifier 442972
SMILES O[C@H](C2)CC[C@@]1(C)C2=CC[C@]([C@@]([H])3CC[C@@]54O[C@@](C[C@H](C)CN6)([H])[C@]6([H])[C@H]5C)([H])[C@@]([H])1CC3=[C@@]4C
InChiKey QASFUMOKHFSJGL-LAFRSMQTSA-N
Appearance White to off-white solid
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Grouped product items
Order: HB2965
Pack PriceQty
1mg
$196
5mg
$746
Smo and hedgehog (Hh) signaling inhibitor. Also depletes stem like cancer cells and induces hESCs into endocrine cells.
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Standard: $35

Hazardous: $35

Shipped on ice: $35

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