Product overview

Name AICAR
Description AMPK activator. Promotes osteogenic differentiation of bone marrow-derived MSCs.
Purity >99%
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Biological Data

Biological description Cell permeable AMP-activated protein kinase (AMPK) activator. Down-regulates insulin receptor expression. Promotes differentiation and mineralization of MC3T3-E1 osteoblastic cells. Also promotes osteogenic differentiation of mensenchymal stem cells and induces astroglial differentiation in neural stem cells. Additionaly induces expression of several key regulators of pulripotency in somatic cells.

Solubility & Handling

Storage instructions -20°C
Solubility overview Soluble in water (75mM) or DMSO (75mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Chemical Data

Chemical name N1-(β-D-Ribofuranosyl)-5-aminoimidaz ole-4-carboxamide
Molecular Weight 258.23
Chemical structure AICAR |  [2627-69-2] Chemical Structure
Molecular Formula C9H14N4O5
CAS Number 2627-69-2
PubChem identifier 17513
SMILES O[C@@H]1[C@@H](CO)O[C@@H](N2C=NC(C(N)=O)=C2N)[C@@H]1O
InChiKey RTRQQBHATOEIAF-UHFFFAOYSA-N
Appearance Off-white solid