Stem cells

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Stem cells are unspecialized cells that are capable of self-renewal through mitotic cell division. They may be induced to form more specialized cells by a process termed cellular differentiation.The main types of stems cells are embryonic stem cells (ESCs) found in blastocysts; adult (or somatic) stem cells, found in adult tissues, induced pluripotent stem cells (iPSCs) and cancer stem cells (CSCs). Small molecule pharmacological tools can be used to manipulate signalling pathways during the in vitro culture of stem cells. These tools can be used to target signaling pathways that control cell proliferation and differentiation. Researchers can save up to 50% on stem cell research tools from Hello Bio - they are around half the price of other suppliers.

View products:  Differentiation | Organoids | Proliferation/Self-renewal | Reprogramming | Stem Cell Signaling View resources: Stem Cell Research Tools & Mini-Reviews

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  1. A 83-01 (HB3218)

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    Description:

    Selective TGF-βRI (ALK5), ALK4 and ALK7 inhibitor. Maintains human hiPSC self renewal, 3D growth matrix component and promotes long-term organoid growth. Aids fibroblast to NSC/cardiomyocyte reprogramming.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $59
    Qty:
    Pack:
    25mg
    Price:
    $265
    Qty:
  2. CHIR 99021 (HB1261)

    Description:

    Potent, selective GSK3 inhibitor and Wnt signaling activator. Commonly used in organoid production and involved in reprogramming MEFs to IPSCs and fibroblasts to mature neurons.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $146
    Qty:
    Pack:
    50mg
    Price:
    $585
    Qty:
  3. Description:

    Potent, selective GSK3 inhibitor and Wnt signaling activator. Commonly used in organoid production and involved in reprogramming MEFs to IPSCs and fibroblasts to mature neurons. Water soluble.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $182
    Qty:
    Pack:
    50mg
    Price:
    $728
    Qty:
  4. DAPT (HB3345)

    1  Review
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    Description:

    γ-secretase inhibitor and classical notch inhibitor. Induces neuronal differentiation. 3D Growth matrix component and used in cerebral organoid differentiation media.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $82
    Qty:
    Pack:
    10mg
    Price:
    $139
    Qty:
    Pack:
    25mg
    Price:
    $346
    Qty:
    Pack:
    50mg
    Price:
    $582
    Qty:
  5. Forskolin (HB1348)

    3  Reviews
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    Description:

    Cell permeable, reversible adenylyl cyclase activator. Neuronal differentiation inducer. Used in production of liver organoids.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $96
    Qty:
    Pack:
    50mg
    Price:
    $406
    Qty:
  6. Description:

    Selective CCK2 agonist. Endogenous peptide.

    Pack:
    250μg
    Price:
    $82
    Qty:
    Pack:
    1mg
    Price:
    $219
    Qty:
  7. IWP 2 (HB0344)

    Description:

    Potent Wnt pathway inhibitor and PORCN inhibitor. Suppresses R1 ESC self-renewal. Used in the production of cardiac organoids.

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $297
    Qty:
  8. IWP 4 (HB3066)

    Description:

    Potent Wnt/β-catenin signaling inhibitor. Induces cardiomyocyte differentiation of hESCs and iPSCs.

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $442
    Qty:
  9. Description:

    Potent, selective ALK2/ALK3 inhibitor which also promotes neural induction of hPSCs. May be used as a component for brain organoid production.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $133
    Qty:
    Pack:
    50mg
    Price:
    $525
    Qty:
  10. PD 0325901 (HB2240)

    Description:

    Potent MEK1 and MEK2 inhibitor. Enhances iPSCs generation. Used in organoid production.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $166
    Qty:
    Pack:
    50mg
    Price:
    $471
    Qty:

Items 1-10 of 14

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