Stem cells
Small molecule pharmacological tools can be used to manipulate signalling pathways during the in vitro culture of stem cells. These small molecules can be used to target signaling pathways that control cell proliferation and differentiation. Researchers can save up to 50% on high purity stem cell research tools such as ROCK inhibitor Y 27632, A83-01 and CHIR 99021 from Hello Bio - they are around half the price of other suppliers.
View products:  Differentiation | Organoids | Proliferation/Self-renewal | Reprogramming | Stem Cell Signaling View resources: Stem Cell Research Tools & Mini-Reviews
Ionomycin free acid (HB1002)
Description:Calcium ionophore. Stimulates cytokine production.
Purity:>98%
IPTG (HB3941)
Description:Protein expression inducer. Frequently used with X-Gal in cloning procedures.
Purity:>99%
Ivermectin (IVM) (HB1958)
Description:α7 nicotinic acetylcholine receptor positive allosteric modulator. Activates GluCI/GlyCI chemogenetic channels. Shows antiviral activity.
Purity:>95%
IWP 2 (HB0344)
Description:Potent Wnt pathway inhibitor and PORCN inhibitor. Suppresses R1 ESC self-renewal. Used in the production of cardiac organoids.
Purity:>98%
IWP 4 (HB3066)
Description:Potent Wnt/β-catenin signaling inhibitor. Induces cardiomyocyte differentiation of hESCs and iPSCs.
Purity:>98%
JC-1 (HB0791)
Description:Mitochondrial membrane potential indicator/dye. Widely used in apoptosis studies.
Purity:>95%
LDN193189 hydrochloride (LDN) (HB5624)
Description:Potent, selective ALK2/ALK3 inhibitor which also promotes neural induction of hPSCs. May be used as a component for brain organoid production.
Purity:>98%