Mitochondrial membrane potential indicator/dye which is widely used in apoptosis studies to monitor mitochondrial health.
It can be used as an indicator of mitochondrial membrane potential in various cell types including neurons and myocytes and also intact tissues and isolated mitochondria.
At low concentrations (due to low mitochondrial membrane potential), JC-1 is predominantly a monomer that yields green fluorescence with emission of 530±15 nm.
At high concentrations (due to high mitochondrial membrane potential), the dye aggregates yielding a red to orange colored emission (590±17.5 nm).
Depolarization is indicated by a decrease the aggregate fluorescent count and hyperpolarization is indicated by an increase.
Allows both qualitative visualization and quantitative detection.
Solubility & Handling
Storage instructions
-20°C
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
![JC-1 [47729-63-5] Chemical Structure](https://cdn.hellobio.com/media/catalog/product//h/b/hb0791.png "JC-1 [47729-63-5]")
Understanding purity and quality - a guide for life scientists
